Genome Sequence of Escherichia coli XH140A, Which Produces l -Threonine
نویسندگان
چکیده
منابع مشابه
Genome sequence of Escherichia coli XH140A, which produces L-threonine.
Here we report the draft annotated genome sequence of Escherichia coli XH140A, which is used to produce l-threonine in industry. The genome sequence will allow the characterization of the molecular mechanisms underlying its beneficial properties.
متن کاملDraft genome sequence of Escherichia coli XH001, a producer of L-threonine in industry.
L-Threonine has been widely used as a supplement in the food, pharmaceutical, and cosmetic industries. Here, we present a high-quality draft annotated genome sequence of Escherichia coli XH001, a producer of L-threonine in industry. Its genome and plasmid sequence will provide clues about the molecular mechanisms underlying its beneficial properties.
متن کاملProduction of L-threonine by auxotrophic mutants of Escherichia coli.
Two auxotrophic mutants of Escherichia coli have been shown to accumulate significant amounts of l-threonine in the culture medium. One mutant, 13071, is deficient in alpha,epsilon-diaminopimelic acid (DAP), and the other, 13070, is deficient in both DAP and methionine. Accumulation of l-threonine by 13071 in a synthetic medium with mannitol as the carbon source at 37 C incubation temperature w...
متن کاملMetabolic engineering of a reduced-genome strain of Escherichia coli for L-threonine production
BACKGROUND Deletion of large blocks of nonessential genes that are not needed for metabolic pathways of interest can reduce the production of unwanted by-products, increase genome stability, and streamline metabolism without physiological compromise. Researchers have recently constructed a reduced-genome Escherichia coli strain MDS42 that lacks 14.3% of its chromosome. RESULTS Here we describ...
متن کاملSystems metabolic engineering of Escherichia coli for L-threonine production
Amino-acid producers have traditionally been developed by repeated random mutagenesis owing to the difficulty in rationally engineering the complex and highly regulated metabolic network. Here, we report the development of the genetically defined L-threonine overproducing Escherichia coli strain by systems metabolic engineering. Feedback inhibitions of aspartokinase I and III (encoded by thrA a...
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ژورنال
عنوان ژورنال: Journal of Bacteriology
سال: 2011
ISSN: 0021-9193,1098-5530
DOI: 10.1128/jb.06011-11